Associate Professor
Psychiatry
Pediatrics
Email Contact Info More Publications
AREAS OF CLINICAL INTEREST
Psychiatric and developmental disorders in children (infancy through early adulthood) including autism, psychiatric complications of medical disorders, abnormally aggressive behavior in children
AREAS OF RESEARCH INTERESTS
A collaboration with the Autism Genetic Resource Exchange (AGRE) to confirm and refine quantitative linkage signals (SRS phenotype) for chromosomal regions potentially containing genetic susceptibility loci for autism.
Longitudinal study of the life course and genetic structure of autistic social impairment.
Preventive intervention program for disadvantaged urban families, in which early parent-child relationships are enhanced in the setting of an infant center, designed to promote normal social development in children.
Follow-up study of temperament and behavior in children from whom cerebrospinal fluid monoamine metabolites were obtained in the neonatal period.
Study of internal working models (mental representations) of attachment in adolescent twins.
SPECIAL POPULATIONS, DATA SETS, AND FACILITIES
Clinical sample of 250 child psychiatric patients with and without autism spectrum conditions enrolled in a longitudinal study of social development.
Epidemiologic sample of twins, originally assessed in 1999, being followed prospectively to study genetic and environmental influences on social development.
Research Publications
Constantino JN, Todd RD (2005 Mar 15). Intergenerational transmission of subthreshold autistic traits in the general population. Biol Psychiatry. 57 (6): 655-60. Full Article >
Ho A, Todd RD, Constantino JN (2005 Feb). Brief report: autistic traits in twins vs. non-twinsa preliminary study. J Autism Dev Disord. 35 (1): 129-33. Full Article >
Constantino JN, Davis SA, Todd RD, Schindler MK, Gross MM, Brophy SL, Metzger LM, Shoushtari CS, Splinter R, Reich W (2003 Aug). Validation of a brief quantitative measure of autistic traits: comparison of the social responsiveness scale with the autism diagnostic interview-revised. J Autism Dev Disord. 33 (4): 427-33. Full Article >
Constantino JN, Gruber CP, Davis S, Hayes S, Passanante N, Przybeck T (2004 May). The factor structure of autistic traits. J Child Psychol Psychiatry. 45 (4): 719-26. Full Article >
Constantino JN, Todd RD (2003 May). Autistic traits in the general population: a twin study. Arch Gen Psychiatry. 60 (5): 524-30. Full Article >
Constantino JN, Hudziak JJ, Todd RD (2003 Apr). Deficits in reciprocal social behavior in male twins: evidence for a genetically independent domain of psychopathology. J Am Acad Child Adolesc Psychiatry. 42 (4): 458-67. Full Article >
Contact Info
John Constantino, M.D.
Office Phone: 314-747-6772
Lab Phone: 314-286-0068
Campus Box: 8134
Fax: 314-747-6777
constantino@wustl.edu
