Professor
Internal Medicine
Cell Biology and Physiology
Email Contact Info More Publications
Mechanisms of Ca induced exocytosis from exci endocrine cells (insulin-secreting pancreatic islet cells and adrenal chromaffin cells) investigated by single cell assays of exocytosis (membrane capacitance measurements, electrochemical amperometry and membrane bound fluorescent dyes). Modulation of exocytosis by other second messengers and by the excitatory neurotoxin alpha-latrotoxin from the black widow spider
Research Publications
Misler S, Dickey A, Barnett DW (2005 Jun 30). Maintenance of stimulus-secretion coupling and single beta-cell function in cryopreserved-thawed human islets of Langerhans. Pflugers Arch. Full Article >
Silva AM, Liu-Gentry J, Dickey AS, Barnett DW, Misler S (2005 Jun 15). alpha-Latrotoxin increases spontaneous and depolarization-evoked exocytosis from pancreatic islet beta-cells. J Physiol. 565 (Pt 3): 783-99. Full Article >
Johnson JD, Han Z, Otani K, Ye H, Zhang Y, Wu H, Horikawa Y, Misler S, Bell GI, Polonsky KS (2004 Jun 4). RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. J Biol Chem. 279 (23): 24794-802. Full Article >
Johnson JD, Kuang S, Misler S, Polonsky KS (2004 May). Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion. FASEB J. 18 (7): 878-80. Full Article >
Johnson JD, Ahmed NT, Luciani DS, Han Z, Tran H, Fujita J, Misler S, Edlund H, Polonsky KS (2003 Apr). Increased islet apoptosis in Pdx1+/- mice. J Clin Invest. 111 (8): 1147-60. Full Article >
Liu J, Misler S (1998 Aug 15). alpha-Latrotoxin alters spontaneous and depolarization-evoked quantal release from rat adrenal chromaffin cells: evidence for multiple modes of action. J Neurosci. 18 (16): 6113-25. Full Article >
Contact Info
Stanley Misler, M.D., Ph.D.
Office Location: 815 Jewish Hosp. (Yalem)
Office Phone: 314-454-7719
Campus Box: 8050
Fax: 314-454-5126
misler@wustl.edu
