Faculty advisor: Harrison Gabel, PhD
Dissertation (2020): Computational analysis of non-CpG DNA methylation in the mammalian nervous system
Related publications
- Kinde, BZ, Wu D, Greenberg ME, Gabel HW. DNA methylation in the gene body influences MeCP2-mediated gene repression. Proc Natl Acad Sci U S A. Dec 13, 2016; pii:201618737. [Epub ahead of print]
- Chen X, Chanda A, Ikeuchi Y, Zhang X, Goodman J, Reddy N, Majidi S, Wu D, Smith S, Godec A, Oldenborg A, Gabel H, Zhao G, Bonni S, Bonni A. The transcriptional regulator SnoN promotes the proliferation of cerebellar granule neuron precursors in the postnatal mouse brain. J Neurosci. Jan 2, 2019; 39(1):44-62. doi: 10.1523/JNEUROSCI.0688-18.2018. Epub Nov 13, 2018.
- Schlosberg CE, Wu DY, Gabel HW, Edwards JR. ME-Class2 reveals context dependent regulatory roles for 5-hydroxymethylcytosine. Nucleic Acids Res. Mar 18, 2019; 47(5):e28. doi: 10.1093/nar/gkz001.
- Clemens AW*, Wu DY*, Moore JR, Christian DC, Zhao G, Gabel HW. MeCP2 represses enhancers through chromosome topology-associated DNA methylation. Molecular Cell. Jan 16, 2020; 77(2):279-293.e8. doi: 10.1016/j.molcel.2019.10.033. Epub Nov 26, 2019.
- Goodman JV, Yamada T, Yang Y, Kong L, Wu DY, Zhao G, Gabel HW, Bonni A. The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain. Nat Commun. Jul 9, 2020; 11(1):3419. doi: 10.1038/s41467-020-17065-z.
- Christian DL*, Wu DY*, Martin JR, Moore JR, Liu YR, Clemens AW, Nettles SA, Kirkland NM, Papouin T, Hill CA, Wozniak DF, Dougherty JD, Gabel HW. DNMT3A haploinsufficiency results in behavioral deficits and global epigenomic dysregulation shared across neurodevelopmental disorders. Cell Rep. Nov 24, 2020; 33(8):108416. doi: 10.1016/j.celrep.2020.108416.
*=equal contribution