Date: Wednesday, November 11, 2026

Time: 8:00 a.m. – 6:00 p.m.

Location: Jeffrey T. Fort Neuroscience Research Building

Fluorescence microscopy image of neuronal cells and branching processes

The Brain Development & Disorders Symposium will bring together leading investigators from Washington University and institutions around the world for a full day exploring advances in brain development and neurodevelopmental disorders. The program will feature scientific presentations spanning genetics, cerebral cortex development, molecular mechanisms, and cognitive and neurological phenotypes, along with poster sessions designed to foster discussion and collaboration.

Hosted by: Department of Neuroscience · Intellectual and Development Disabilities Research Center (IDDRC) · Department of Neurology, Division of Pediatric and Developmental Neurology

Small laboratory animal standing upright

Supported by the McDonnell Center for Cellular and Molecular Neurobiology


2026 Brain Development & Disorders Symposium Registration

2026 Brain Development & Disorders Symposium Registration
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2026 Symposium Program of Events

8:30 – 8:40 am I Opening Remarks : Linda Richards (Welcome) & Natasha Marrus (IDDRC Overview)

Session 1: Genetics of Neurodevelopmental Disorders

Chair: Dustin Baldridge

8:40 – 8:55 amJenn Cremins, WashU
“Mechanisms and Consequences of Chromatin Loop Memory In Vivo”
8:55 – 9:10amTychele Turner, WashU
“The Noncoding Genome in Cortical Development and Autism”
9:10 – 9:25 amHarrison Gabel, WashU
“Probing Neurodevelopmental Disorders at Single Cell Resolution in the Brain”
9:25 – 9:40 amLinda Richards, WashU
“Molecular Mechanisms Governing Cerebral Cortex Formation and Their Disruption in Human Developmental Disorders”

9:40 – 10:00 am I Morning Tea Break & Poster Session

Session 2: Early Development of the Cerebral Cortex

Chair: Liz Pollina

10:00 – 10:45 amChiaki Ohtaka-Maruyama, Tokyo Metropolitan Inst. of Medical Science
“Molecular Basis of Subplate Layer Expansion in Human Fetal Brain Development”
10:45 – 11:30 amAlessandra Pierani, INSERM, Paris
“Transient Moving Organizers: Life and Death from Cortical Development to Disease Treatment”
11:30 am – 12:15 pmTakako Kikkawa, Tohoku University, Sendai
“mRNA Localization and Kinesin Function in Radial Glia: Implications for Neurodevelopment”
12:15 – 12:30 pmRafael Galindo, WashU
“Talk Title: TBD”

12:30 – 2:00 pm I Lunch & Poster Session

Session 3: Molecular Mechanisms of Developmental Brain Disorders

Chair: Natasha Marrus

2:00 – 2:45 pmJeffrey Russ, Duke University Medical Center
“Untangling Cortical Intratelencephalic (IT) Neurons in Development and Disease”
2:45 – 3:00 pmJoe Dougherty, WashU
“Metabolite-Gene Expression Interactions in the Developing Human Cortex”
3:00 – 3:15 pmJason Yi, WashU
“Dissecting Neuronal Growth Suppression in Angelman Syndrome”
3:15 – 3:30 pmKris Kroll, WashU
“Tatton-Brown-Rahman Syndrome-Associated DNMT3A Mutations De-repress Cortical Interneuron Differentiation to Disrupt Neuronal Network Function”

3:30 – 3:50 pm I Afternoon Tea Break & Poster Session

Session 4: Cognitive & Neurological Phenotypes in Developmental Brain Disorders

Chair: Chris Smyser

3:50 – 4:35 pmMitsuhiro Kato, Showa Medical University, Tokyo
“Targeted Therapy and AI-Driven Diagnosis: Moving Beyond the Molecular Pathogenesis of Cortical Dysplasias and Functional Neurodevelopmental Disorders”
4:35 – 4:50 pmCynthia Rogers, WashU
“Preterm Birth, Executive Function, and the Preterm Behavioral Phenotype”
4:50 – 5:05 pmAdam Kepecs, WashU
5:05 – 5:20 pmChad Sylvester, WashU
“Brain Network Development in Children at Risk for Anxiety Disorders”
5:20 – 5:35 pmHysell Oviedo, WashU
“Out of Sync: Building and Breaking Hemispheric Specialization”

5:35 – 5:45 pm I Closing Remarks: Linda Richards