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Category: Research

‘Gain-of-function’ mutation spawns autism traits (Links to an external site)

July 31, 2023October 18, 2023
Embryonic mice with a hyperactivating mutation in UBE3A show increased numbers of a specific subset of inhibitory interneurons (green) in the brain’s outer layer.

Assistant Professor Jason Yi’s latest work on UBE3A is highlighted in Spectrum.

Humans will trade pain for useless information (Links to an external site)

July 12, 2023October 18, 2023
A hand flipping a gold coin on a blue background

Read comments from Dr. Ethan Bromberg-Martin, a senior scientist in Ilya Monosov’s lab, on a new study about the value of inconsequential knowledge.

Jason Yi and Harrison Gabel each receive SFARI Pilot Awards to study autism-related disorders

July 11, 2023October 18, 2023
Jason Yi and Harrison Gabel

In the Yi Lab, the funding will go to developing an inhibitor of the protein UBE3A, which causes neurodevelopmental disorders. The Gabel Lab is establishing a novel platform to examine brain connectivity and gene disruption in a model of Rett Syndrome.

The shape of your brain may strongly influence your thoughts and behavior, study finds (Links to an external site)

June 2, 2023December 14, 2023
A man points at brain scans on a computer screen

Read Dr. David Van Essen’s comments on the new study in Nature.

Amy Christensen receives Helen Hay Whitney Fellowship   

May 19, 2023May 7, 2025
Amy Christensen and Washington University shield logo

The three-year award will support Dr. Christensen’s postdoctoral research in Adam Kepecs’ lab on the neural computations underlying uncertainty in decision-making.

Two Department of Neuroscience scholars receive grants from McDonnell Center for Systems Neuroscience

May 16, 2023December 14, 2023
Tom Franken and Alessandro Livi

Assistant Professor Tom Franken will explore how the brain distinguishes objects from shadows, and Alessandro Livi, a postdoctoral researcher, will map the brain networks underlying economic decision-making.

WashU, JuliaHub and MIT developers unveil major update to Julia programming language (Links to an external site)

May 11, 2023December 14, 2023
Tim Holy

Professor Tim Holy and colleagues produced Julia 1.9, which eliminates slow startup times and lowers the barriers to even wider adoption of this popular tool.

Gabel Lab identifies molecular links between Sotos and Tatton Brown Rahman Syndromes

May 4, 2023December 14, 2023
Nicole Hamagami and Dennis Wu

The two rare genetic diseases, which have striking phenotypic similarities, lead to similar downstream consequences on gene activity in neurons of mouse models.

Kristen Prufrock awarded grant to study how tooth formation affects face shape

April 25, 2023December 14, 2023
Kristen Prufrock with Washington University shield logo on red background

As part of a collaborative team, Prufrock will produce models of how developing teeth influence facial bone growth in multiple primate species.

Martha Bagnall receives R01 grant from National Institute of Neurological Disorders and Stroke

April 14, 2023December 14, 2023
Martha Bagnall

The Bagnall Lab is creating a map of connections along the length of neurons in the spinal cord to understand their function in movement.

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