Adam Clemens, PhD

Adam Clemens, PhD

Scientist, Ascidian Therapeutics

Faculty advisor: Harrison Gabel, PhD

Dissertation (2020): Understanding the roles of DNA methylation and MeCP2 in neuronal enhancer control

Related publications

Clemens AW*, Wu DY*, Moore JR, Christian DC, Zhao G, Gabel HW. MeCP2 represses enhancers through chromosome topology-associated DNA methylation. Molecular Cell. Jan 16, 2020; 77(2):279-293.e8. doi: 10.1016/j.molcel.2019.10.033. Epub Nov 26, 2019.

Clemens AW, Gabel HW. Emerging Insights into the Distinctive Neuronal Methylome. Trends Genet. Nov 2020; 36(11):816-832. doi: 10.1016/j.tig.2020.07.009. Epub Aug 21, 2020. 

Christian DL*, Wu DY*, Martin JR, Moore JR, Liu YR, Clemens AW, Nettles SA, Kirkland NM, Papouin T, Hill CA, Wozniak DF, Dougherty JD, Gabel HW. DNMT3A haploinsufficiency results in behavioral deficits and global epigenomic dysregulation shared across neurodevelopmental disorders. Cell Rep. Nov 24, 2020; 33(8):108416. doi: 10.1016/j.celrep.2020.108416.