Matthew Thimgan, PhD

Matthew Thimgan, PhD

Associate Professor and Director, Laboratory of Sleep Biology, Missouri University of Science and Technology

Faculty advisor: Paul Shaw, PhD

Postdoctoral fellow, 2005-2010

Related publications

  • Seugnet L, Suzuki Y, Thimgan M, Donlea J, Gimbel SI, Gottschalk L, Duntley SP, Shaw PJ. Identifying sleep regulatory genes using a Drosophila model of insomnia. J Neurosci. 2009 Jun 3;29(22):7148-57. doi: 10.1523/JNEUROSCI.5629-08.2009.
  • Thimgan MS, Suzuki Y, Seugnet L, Gottschalk L, Shaw PJ. The perilipin homologue, lipid storage droplet 2, regulates sleep homeostasis and prevents learning impairments following sleep loss. PLoS Biol. 2010 Aug 31;8(8):e1000466. doi: 10.1371/journal.pbio.1000466.
  • Thimgan MS, Duntley SP, Shaw PJ. Changes in gene expression with sleep. J Clin Sleep Med. 2011 Oct 15;7(5 Suppl):S26-7. doi: 10.5664/JCSM.1352.
  • Donlea JM, Thimgan MS, Suzuki Y, Gottschalk L, Shaw PJ. Inducing sleep by remote control facilitates memory consolidation in Drosophila. Science. 2011 Jun 24;332(6037):1571-6. doi: 10.1126/science.1202249.
  • Donlea J, Leahy A, Thimgan MS, Suzuki Y, Hughson BN, Sokolowski MB, Shaw PJ. Foraging alters resilience/vulnerability to sleep disruption and starvation in Drosophila. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2613-8. doi: 10.1073/pnas.1112623109. Epub 2012 Jan 30.
  • Thimgan MS, Gottschalk L, Toedebusch C, McLeland J, Rechtschaffen A, Gilliland-Roberts M, Duntley SP, Shaw PJ. Cross-translational studies in human and Drosophila identify markers of sleep loss. PLoS One. 2013 Apr 24;8(4):e61016. doi: 10.1371/journal.pone.0061016. PMID: 23637783; PMCID: PMC3634862.
  • Dissel S, Seugnet L, Thimgan MS, Silverman N, Angadi V, Thacher PV, Burnham MM, Shaw PJ. Differential activation of immune factors in neurons and glia contribute to individual differences in resilience/vulnerability to sleep disruption. Brain Behav Immun. 2015 Jul;47:75-85. doi: 10.1016/j.bbi.2014.09.019. Epub 2014 Oct 30.
  • Thimgan MS, Seugnet L, Turk J, Shaw PJ. Identification of genes associated with resilience/vulnerability to sleep deprivation and starvation in Drosophila. Sleep. 2015 May 1;38(5):801-14. doi: 10.5665/sleep.4680.
  • Thimgan MS, Toedebusch C, McLeland J, Duntley SP, Shaw PJ. Excessive daytime sleepiness is associated with changes in salivary inflammatory genes transcripts. Mediators Inflamm. 2015;2015:539627. doi: 10.1155/2015/539627. Epub 2015 Mar 22.
  • Seugnet L, Dissel S, Thimgan M, Cao L, Shaw PJ. Identification of genes that maintain behavioral and structural plasticity during sleep loss. Front Neural Circuits. 2017 Oct 23;11:79. doi: 10.3389/fncir.2017.00079.