Xiaoying Chen, PhD

Xiaoying Chen, PhD

Postdoctoral Research Associate, Washington University

Faculty advisor: Azad Bonni, PhD

Postdoctoral fellow, 2017-2019

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Related publications

  • Chen X, Chanda A, Ikeuchi Y, Zhang X, Goodman JV, Reddy NC, Majidi SP, Wu DY, Smith SE, Godec A, Oldenborg A, Gabel HW, Zhao G, Bonni S, Bonni A. The Transcriptional regulator SnoN promotes the proliferation of cerebellar granule neuron precursors in the postnatal mouse brain. J Neurosci. 2019 Jan 2;39(1):44-62. doi: 10.1523/JNEUROSCI.0688-18.2018. Epub 2018 Nov 13.
  • Smith SE, Chen X, Brier LM, Bumstead JR, Rensing NR, Ringel AE, Shin H, Oldenborg A, Crowley JR, Bice AR, Dikranian K, Ippolito JE, Haigis MC, Papouin T, Zhao G, Wong M, Culver JP, Bonni A. Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway. Nat Commun. 2020 Dec 2;11(1):6164. doi: 10.1038/s41467-020-19915-2.
  • Krishnan N, Chen X, Donnelly-Roberts D, Mohler E.G, Holtzman D. M, Gopalakrishnan, S. M. Small molecule phenotypic screen identifies novel regulators of LDLR expression. 2020. ACS Chem Biol.15, 3262-3274.
  • Chen X, Zhang B, Wang T, Bonni A, Zhao G. Robust principal component analysis for accurate outlier sample detection in RNA-Seq data. BMC Bioinformatics. 2020 Jun 29;21(1):269. doi: 10.1186/s12859-020-03608-0.
  • Chen X, Du Y, Broussard GJ, Kislin M, Yuede CM, Zhang S, Dietmann S, Gabel H, Zhao G, Wang SS, Zhang X, Bonni A. Transcriptomic mapping uncovers Purkinje neuron plasticity driving learning. Nature. 2022 May;605(7911):722-727. doi: 10.1038/s41586-022-04711-3. Epub 2022 May 11.
  • Chen X, Holtzman D. Emerging roles of innate and adaptive immunity in Alzheimer’s Disease. Immunity. 2022 Dec 13;55(12):2236-2254. doi: 10.1016/j.immuni.2022.10.016. Epub 2022 Nov 8.
  • Chen X, Firulyova M, Manis M, Herz J, Smirnov I, Aladyeva E, Wang C, Bao X, Finn M, Hu H, Shchukina I, Kim M, Yuede C, Kipnis J, Artyomov M, Ulrich J, Holtzman D. Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy. 2023. Nature. 615, 668-677