Functional characterization of the dural sinuses as a neuroimmune interface

Functional characterization of the dural sinuses as a neuroimmune interface

Rustenhoven, J., Drieu, A., Mamuladze, T., de Lima, K. A., Dykstra, T., Wall, M., Papadopoulos, Z., Kanamori, M., Salvador, A. F., Baker, W., Lemieux, M., Da Mesquita, S., Cugurra, A., Fitzpatrick, J., Sviben, S., Kossina, R., Bayguinov, P., Townsend, R. R., Zhang, Q., Erdmann-Gilmore, P., Smirnov, I., Beatriz-Lopes, M., Herz, J., Kipnis, J., Feb 18 2021, In: Cell. 184, 4, p. 1000-1016.e27

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Gabel Lab

Epigenetic mechanisms in the brain

PI: Harrison Gabel, PhD

The Gabel Lab studies molecular mechanisms of gene regulation that contribute to development and plasticity in the mammalian brain, and how disruption of these mechanisms can lead to neurological disease.

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Goodhill Lab

Brain development

PI: Geoffrey Goodhill, PhD

The Goodhill Lab is interested in how brains process information, particularly during development. Our current focus is on the development of neural coding in the zebrafish brain. We are addressing this using a combination of behavioral analysis, calcium imaging of neural activity, and mathematical/computational modeling.

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Han Lab

Learning & memory in the hippocampus

PI: Edward Han, PhD

The Han lab studies learning and memory processes in the hippocampus. The lab investigates the cellular and neuronal circuit activity supporting spatial navigation learning in mice. Major approaches in the lab include in vivo two- photon calcium imaging during virtual reality behavioral tasks, in vivo electrophysiology, optogenetics, and computational modeling.

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Holy Lab

Olfactory circuits, technology & computation

PI: Timothy Holy, PhD

The Holy Lab combines a focus on understanding circuits and behavior with a willingness to pioneer new technologies to address the major challenges in the field. The lab's major scientific focus is on the olfactory system of mice. We choose this system because it presents a tractable “playground” for so many of the questions of modern neuroscience.

IDDRC seminar series

IDDRC seminar series

The Department of Neuroscience and the Intellectual and Developmental Disabilities Research Center (IDDRC) host the monthly IDDRC seminar series that focuses on research on developmental disorders.

Jean Holowach Thurston

Jean Holowach Thurston

Set standards for pediatric epilepsy research

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Kepecs Lab

Reverse engineering cognition: Neurons to psychiatry

PI: Adam Kepecs, PhD

The long-term goal of the Kepecs Lab is to reverse engineer the computational and neurobiological processes underlying cognition and decision-making and apply these insights to biological psychiatry.

Lee Nelken Robins

Lee Nelken Robins

Leader in the development of diagnostic criteria for psychiatric diagnoses

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Li Lab

Neuroimmunology & microglial biology

PI: Tristan Qingyun Li, PhD

The Li Lab is broadly interested in neuroimmunology with a focus on microglial biology. Particularly, the lab is interested in combining cutting-edge single-cell genomic technologies with in vitro and in vivo genetic, molecular and cellular tools to investigate microglial development, heterogeneity and mechanisms of neuro-immune interactions underlying brain structure and disease.