Yi Lab publishes study in Nature revealing molecular players in Angelman Syndrome

Researchers have shown in mice that slowed brain growth in Angelman’s syndrome is caused by elevated levels of a molecule called asparagine synthetase (green). NeuN (red), a marker for mature neurons, is stained here as well as a DAPI counterstain to show DNA (blue). Image courtesy Jason Yi.

Angelman Syndrome impacts roughly 1 in 20,000 births. It is a neuro-genetic disorder that impacts patients’ movement, sleep, and cognitive function. There is no cure for Angelman Syndrome, and often patients live as long as anyone else, but with far more difficulty due to the seizures, intellectual disability, and speech impairment (among other symptoms) caused […]

Han Lab publishes study revealing neuronal circuit for remembering rewarding places

Neuron cells imaged under a microscope in a wide array of colors against a black and white background.

Cognitive maps help us understand where we are, and remember how to navigate the world. For example, your brain (specifically, your hippocampus) has a map of your home – where tofind the kitchen, the bathroom, the bedroom, and so on. But it’s also important for your mental map to include the locations of things you […]