A study of human brain tissue by Guoyan Zhao and colleagues identifies genetic activity in microglia and astrocytes related neurodegeneration and neuropathology among individuals with Alzheimer or Parkinson disease.
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Cavalli Lab describes immune cells that promote nerve regeneration
After an injury to dorsal root ganglion neurons adjacent to the spinal cord, resident macrophages work with satellite glial cells to heal damaged axons.
Daily activity schedules mapped in the Drosophila brain
Cellular circuits downstream from circadian pacemaker neurons direct normal daily rhythms of feeding, mating and sleep.
Zebrafish advance as a model organism for Fragile X Syndrome
A new study from the Goodhill Lab finds the genetic variant underlying an autism disorder causes changes in fish’s social behavior, preference in visual environment, and neural activity.
Taghert Lab identifies off switch for a set of circadian clock–controlled behaviors in flies
Phosphorylation of a receptor controls how messages from the neuropeptide PDF—which influence dawn and dusk activities in Drosophila—are curtailed on a daily basis to adapt the circadian clock to changing daylight.
People missing all or part of the connection between their brain hemispheres are more persuadable
A study of individuals with congenital corpus callosum dysgenesis suggests they face social difficulties due to being more easily influenced and less aware of being tricked.
Circadian pacemaker neurons exhibit two linked calcium cycles
The slow and fast rhythms reflect distinct cellular processes yet nevertheless have a co-phasic relationship.
Study finds key similarities between rodent and human satellite glial cells
SGCs have been the subject of intense scrutiny for their involvement in inflammation, pain and nerve injury. The results confirm that rodents are a reliable model for translational research on these cells.
Protein linked to intellectual disability has complex role (Links to an external site)
Finding therapies for fragile X may depend on understanding the many ways the protein’s loss affects the brain.
New primer on logistic models for research in decision neuroscience
Camillo Padoa-Schioppa, PhD, has developed a manual of tools for analysis of economic choices.