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Category: Research

Paul Taghert awarded $1.9 million Outstanding Investigator Award

April 14, 2023December 14, 2023
Paul Taghert and Washington University shield logo

Taghert’s group aims to determine how circadian pacemaker cells in the brain control behavior and physiology that peak at different times.

Researchers receive Alzheimer’s Association funding (Links to an external site)

April 6, 2023December 14, 2023
Ibrahim Saliu next to Washington University shield logo

Ibrahim Saliu, a postdoctoral researcher in the Department of Neuroscience, has received a $200,000 grant from the Alzheimer’s Association to study the role of astrocytes in neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

Assistant Professor Tristan Qingyun Li receives R01 grant

April 5, 2023December 14, 2023
tristan qingyun li

The project will investigate the contributions of subsets of microglia—the brain’s immune cells—to Alzheimer’s disease.

Transcriptomic changes in glia linked to specific neurodegenerative diseases

March 2, 2023December 14, 2023
mmunohistochemistry staining of activated microglia in putamen of an individual with AD (microglia labeled by marker protein P2RY12, brown, and activation indicated by TREM2 transcripts, red)

A study of human brain tissue by Guoyan Zhao and colleagues identifies genetic activity in microglia and astrocytes related neurodegeneration and neuropathology among individuals with Alzheimer or Parkinson disease.

Cavalli Lab describes immune cells that promote nerve regeneration

February 10, 2023December 14, 2023
Dorsal root ganglion stained with TUJ1 (neuron, cyan) and IBA1 (macrophages, red)

After an injury to dorsal root ganglion neurons adjacent to the spinal cord, resident macrophages work with satellite glial cells to heal damaged axons.

Daily activity schedules mapped in the Drosophila brain

January 17, 2023March 6, 2023
Diagram illustrating the functional connections between circadian pacemaker neurons, downstream dopaminergic and neurosecretory centers, and daily behaviors

Cellular circuits downstream from circadian pacemaker neurons direct normal daily rhythms of feeding, mating and sleep.

Some dinos may have been as brainy as modern primates, controversial study argues (Links to an external site)

January 12, 2023March 6, 2023
Ashley Morhardt

Read Dr. Ashley Morhardt’s take on the paper in an article in Science.

Zebrafish advance as a model organism for Fragile X Syndrome

January 9, 2023March 6, 2023
A zebrafish with its nervous system fluorescently labeled in green and red hunts a paramecium, fluorescently labeled in green

A new study from the Goodhill Lab finds the genetic variant underlying an autism disorder causes changes in fish’s social behavior, preference in visual environment, and neural activity.

Glia: Unsung heroes of the nervous system (Links to an external site)

January 3, 2023March 6, 2023
Katie Lefton and gray Washington University shield logo

Read graduate student Katie Lefton’s article in Science Today about astrocytes, microglia, and satellite glial cells.

David Van Essen listed as Highly Cited Researcher for eighth consecutive year

December 9, 2022March 6, 2023
David Van Essen

Matthew Glasser, a former graduate student of Van Essen and currently an Instructor in Radiology, also made the 2022 list.

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Department of Neuroscience

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